The East Antarctic Ice Sheet also reached its maximum extent several millennia before the global LGM.
In numerous mountainous regions at high-, mid- and low-latitudes across the world, glaciers reached their maximum extent before Marine Isotope Stage (MIS) 2, in MIS 5, 4 and 3.
Historians seem to agree that the wheel and axle were invented around 3500 B. 60 is divisible by 1,2,3,4,5,6,10,12,15,20,30 and 60 making it more convenient than using a base 10 decimal system when working with fractions.
Despite decimalisation, we still use these sexagesimal measures today.
The Mesopotamians discovered glass, probably from glass beads in the slag resulting from experiments with refining metallic ores.
Egypt was also home to Imhotep the first man of science in recorded history. both of which refer to earlier works attributed to Imhotep. The process for making wrought iron was discovered by the Hittites, in Northern Mesopotamia and Southern Anatolia (now part of Eastern Turkey), who heated iron ore in a charcoal fire and hammered the results into wrought (worked) iron. Recorded in the Bible, Book of Exodus, Chapter 39, Verse 3, - "And they did beat the gold into thin plates, and cut it into wires, to work it. Its construction is described in great detail in the book of Exodus and according to the Bible and Jewish legend it was endowed with miraculous powers including emitting sparks and fire and striking dead Aaron's sons and others who touched it.
He was the world's first named architect and administrator who around 2725 B. built the first pyramid ever constructed, the Stepped Pyramid of Saqqara. The first outlines surgical treatments for various wounds and diseases and the second contains 877 prescriptions and recipes for treating a variety of medical conditions making Imhotep the world's first recorded physician. The earliest evidence of the art of stencilling used by the Egyptians. in the fine linen, with cunning work." The Egyptians also made coarse glass fibres as early as 1600 B. and fibers survive as decorations on Egyptian pottery dating back to 1375 B. It was basically a wooden box of acacia wood lined with gold and also overlaid on the outside with gold.