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Persistently prolonged QT intervals may increase the risk of malignant arrhythmias.

quinidine, amiodarone, sotalol, dofetilide) • some antipsychotics (e.g. erythromycin) • some antihistamines • some quinolone antibiotics (e.g.

moxifloxacin) The above list is not exhaustive and other individual drugs known to significantly increase QT interval (e.g. Drugs known to cause electrolyte disturbances such as thiazide diuretics (hypokalaemia) and drugs known to increase the plasma concentration of flupentixol should also be used with caution as they may increase the risk of QT prolongation and malignant arrythmias (see section 4.4).

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